Achilleas Theocharis | Mathematical Biology | Best Researcher Award

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Prof. Achilleas Theocharis | Mathematical Biology | Best Researcher Award

Professor of Biochemistry & Molecular Biology at Department of Chemistry, University of Patras, Greece

Professor Achilleas D. Theocharis, Ph.D., is a renowned expert in extracellular matrix pathobiology and cancer signaling, serving as Professor of Biochemistry & Molecular Biology at the University of Patras 🎓. With over 116 peer-reviewed publications, more than 13,750 citations, and an inspiring h-index of 54, his impactful research is globally recognized 📚. He has led and supported 19 international/national funded projects, delivered 27 invited lectures, and organized FEBS Advanced Lecture Courses across Europe 🌍. A committed mentor, he has supervised numerous Ph.D. and M.Sc. students, guiding the next generation of scientists 👩‍🔬👨‍🔬. Prof. Theocharis holds key leadership roles, including Department Head and Vice President of the Hellenic Society of Biochemistry & Molecular Biology, and actively serves on editorial boards of prestigious journals 🏅. Known for scholarly excellence, international collaboration, and academic service, he is a standout candidate for the Best Researcher Award 🏆.

Professional Profile 

🎓 Education

Prof. Theocharis earned his Diploma in Chemistry (1994) and Ph.D. in Biochemistry (2000) from the University of Patras, Greece. His early academic journey included pivotal research experiences at prestigious institutions, notably a visiting scientistship at Lund University (1995) and Karolinska Institute (1999–2003), deepening his expertise in immunology, pathology, and cell biology. These formative years fostered a rigorous scientific foundation in extracellular matrix (ECM) biology and cancer research. The immersion in both Greek and Swedish biomedical centers equipped him with exceptional analytical and experimental skills. This strong educational grounding laid the path for his subsequent leadership in matrix pathobiology and translational oncology. Prof. Theocharis remains engaged in continuous learning and scientific excellence, reflected in his extensive academic collaborations and breakthroughs in molecular medicine 🧬.

💼 Professional Experience

Prof. Theocharis is currently Professor of Biochemistry & Molecular Biology at the University of Patras, directing the Biochemistry, Biochemical Analysis & Matrix Pathobiology Research Group. His academic career includes roles from Lecturer to Associate Professor (ref. 2003–2019), enriched by visiting professorships at Uppsala, Karolinska, and Paris 12. He has served in key leadership roles — Department Head, University Senate member, and Vice President of the Hellenic Society of Biochemistry & Molecular Biology. Through these positions, he has helped design academic strategies, foster national/international research networks, and support Erasmus programs. As a mentor, he has guided dozens of undergraduate, M.Sc., and Ph.D. students. His professional journey exemplifies dedication to institutional growth, teaching excellence, administrative leadership, and building global scientific bridges 🌐.

🔬 Research Interests

Prof. Theocharis specializes in extracellular matrix pathobiology, cancer biology, cell signaling, and molecular drug targeting. His research explores how ECM components regulate cell behavior, drive cancer progression, and influence therapy responsivity. By dissecting molecular signaling pathways and ECM–cell communication, his work informs drug discovery strategies and new therapeutic targets. He is particularly focused on proteoglycans, serglycin, and matrix metalloproteinases as key regulators of tumor metastasis and microenvironment modulation. With a systems biology mindset, he bridges biochemistry, molecular biology, and translational oncology to address critical challenges in disease treatment and resistance. His prolific output advances basic molecular understanding and paves the way for novel anti-cancer interventions 👩‍🔬🧠.

🏅 Awards & Honors

Prof. Theocharis’s career is marked by numerous accolades, including awards from the Hellenic Society of Biochemistry & Molecular Biology (2000, 2017) and invitations to deliver FEBS Advanced Lecture Courses (2018). He received a prestigious French Government scholarship as a Visiting Professor (2012) and fellowships from FEBS (2002, 2008) and the Hellenic Scholarship Foundation. He also earned the Leonidas Zervas Foundation Award (1999). These honors reflect recognition from both national and international communities for his leadership in extracellular matrix research and cancer biology. Regular invitations as a keynote speaker at FEBS events and inclusion in high-profile research evaluation panels underscore the broader impact and esteem of his scholarly work 🌟.

🛠️ Research Skills

Prof. Theocharis possesses expert-level skills in molecular biology, biochemistry, cell signaling, and extracellular matrix analyses. He is proficient in proteomics, immunohistochemistry, gene editing, and advanced imaging techniques. His computational biology expertise complements his experimental work, enabling in-depth pathway analysis and data-driven insight. Prof. Theocharis excels in multi-disciplinary collaboration, having co-led over 19 national and international grants. As an active peer reviewer and academic editor, he demonstrates exceptional critical thinking, scholarly rigor, and ethical standards. His dual experience in laboratory research and academic management ensures scientific innovation, reproducibility, and knowledge dissemination. He is known for designing cutting-edge protocols, training students, and advancing translational cancer research and ECM modeling 🧪🔍.

Publications Top Note 📝

  • Title: The extracellular matrix as a multitasking player in disease
    Authors: AD Theocharis, D Manou, NK Karamanos
    Year: 2019
    Citations: 483
    Source: The FEBS Journal, 286(15), 2830–2869

  • Title: Proteoglycan chemical diversity drives multifunctional cell regulation and therapeutics
    Authors: NK Karamanos, Z Piperigkou, AD Theocharis, H Watanabe, M Franchi, …
    Year: 2018
    Citations: 352
    Source: Chemical Reviews, 118(18), 9152–9232

  • Title: Syndecans–key regulators of cell signaling and biological functions
    Authors: NA Afratis, D Nikitovic, HAB Multhaupt, AD Theocharis, JR Couchman, …
    Year: 2017
    Citations: 314
    Source: The FEBS Journal, 284(1), 27–41

  • Title: Cross-talk between estradiol receptor and EGFR/IGF-IR signaling pathways in estrogen-responsive breast cancers: focus on the role and impact of proteoglycans
    Authors: SS Skandalis, N Afratis, G Smirlaki, D Nikitovic, AD Theocharis, …
    Year: 2014
    Citations: 257
    Source: Matrix Biology, 35, 182–193

  • Title: Matrix modeling and remodeling: A biological interplay regulating tissue homeostasis and diseases
    Authors: NK Karamanos, AD Theocharis, T Neill, RV Iozzo
    Year: 2019
    Citations: 251
    Source: Matrix Biology, 75, 1–11

  • Title: Proteoglycans remodeling in cancer: Underlying molecular mechanisms
    Authors: AD Theocharis, NK Karamanos
    Year: 2019
    Citations: 211
    Source: Matrix Biology, 75, 220–259

  • Title: Pancreatic carcinoma is characterized by elevated content of hyaluronan and chondroitin sulfate with altered disaccharide composition
    Authors: AD Theocharis, ME Tsara, N Papageorgacopoulou, DD Karavias, …
    Year: 2000
    Citations: 208
    Source: Biochimica et Biophysica Acta (BBA) – Molecular Basis of Disease, 1502(2), 201–206

  • Title: Estrogen receptor alpha mediates epithelial to mesenchymal transition, expression of specific matrix effectors and functional properties of breast cancer cells
    Authors: P Bouris, SS Skandalis, Z Piperigkou, N Afratis, K Karamanou, AJ Aletras, …
    Year: 2015
    Citations: 200
    Source: Matrix Biology, 43, 42–60

  • Title: Serglycin is involved in TGF-β induced epithelial-mesenchymal transition and is highly expressed by immune cells in breast cancer tissue
    Authors: M Tellez-Gabriel, X Tekpli, TM Reine, B Hegge, SR Nielsen, M Chen, …
    Year: 2022
    Citations: 17
    Source: Frontiers in Oncology, 12, 868868

  • Title: Preclinical evaluation of zoledronate using an in vitro mimetic cellular model for breast cancer metastatic bone disease
    Authors: PG Dedes, I Kanakis, C Gialeli, AD Theocharis, T Tsegenidis, D Kletsas, …
    Year: 2013
    Citations: 16
    Source: Biochimica et Biophysica Acta (BBA) – General Subjects, 1830(6), 3625–3634

  • Title: Pathophysiology and pharmacological targeting of tumor-induced bone disease: current status and emerging therapeutic interventions
    Authors: VT Labropoulou, AD Theocharis, A Symeonidis, SS Skandalis, …
    Year: 2011
    Citations: 15
    Source: Current Medicinal Chemistry, 18(11), 1584–1598

  • Title: IGF-I affects glycosaminoglycan/proteoglycan synthesis in breast cancer cells through tyrosine kinase-dependent and-independent pathways
    Authors: TN Mitropoulou, AD Theocharis, D Nikitovic, NK Karamanos, …
    Year: 2004
    Citations: 14
    Source: Biochimie, 86(4–5), 251–259

  • Title: Resistance to hormone therapy in breast cancer cells promotes autophagy and EGFR signaling pathway
    Authors: KE Siatis, E Giannopoulou, D Manou, P Sarantis, MV Karamouzis, …
    Year: 2023
    Citations: 11
    Source: American Journal of Physiology – Cell Physiology, 325(3), C708–C720

  • Title: Hyaluronan determination: Biological significance & analytical tools
    Authors: CJ Malavaki, I Kanakis, AD Theocharis, FN Lamari, NK Karamanos
    Year: 2007
    Citations: 11
    Source: Current Pharmaceutical Analysis, 3(2), 117–128

  • Title: Synthesis and antiproliferative activity of novel dehydroabietic acid-chalcone hybrids
    Authors: S Grigoropoulou, D Manou, AI Antoniou, A Tsirogianni, C Siciliano, …
    Year: 2022
    Citations: 10
    Source: Molecules, 27(11), 3623

  • Title: Cellular microenvironment in human pathologies
    Authors: D Vigetti, M Götte, MSG Pavão, AD Theocharis
    Year: 2013
    Citations: 10
    Source: BioMed Research International, 2013, 946958

  • Title: Immunological studies of sheep brain keratan sulphate proteoglycans
    Authors: N Papageorgakopoulou, AD Theocharis, SS Skandalis, DH Vynios, …
    Year: 2002
    Citations: 10
    Source: Biochimie, 84(12), 1223–1226

  • Title: Isolation and analysis of a novel acidic polysaccharide from the case of squid pen
    Authors: AD Theocharis, NK Karamanos, T Tsegenidis
    Year: 1999
    Citations: 10
    Source: International Journal of Biological Macromolecules, 26(1), 83–88

  • Title: Immunization with specific polysaccharide antigen reduces alterations in corneal proteoglycans during experimental slime-producing Staphylococcus epidermidis keratitis
    Authors: CD Georgakopoulos, AM Exarchou, SP Gartaganis, F Kolonitsiou, …
    Year: 2006
    Citations: 9
    Source: Current Eye Research, 31(2), 137–146

  • Title: Keratan sulfate‐containing proteoglycans in sheep brain with particular reference to phosphacan and synaptic vesicle proteoglycan isoforms
    Authors: EA Sinouris, SS Skandalis, V Kilia, AD Theocharis, DA Theocharis, …
    Year: 2009
    Citations: 8
    Source: Biomedical Chromatography, 23(5), 455–463

🏁 Conclusion

Prof. Achilleas D. Theocharis is a distinguished leader in extracellular matrix science and cancer biology. With an impressive portfolio — 116 publications, 13,750 citations, dual h-indices (Scopus: 47; Google Scholar: 54), and 27 invited lectures — he exemplifies research excellence 🌟. His contributions span from fundamental mechanism elucidation to clinical relevance, supported by strong mentorship and institutional leadership. His roles in national/international scientific societies, editorial boards, and grant panels underscore his collaborative vision. While continuing to grow in translational impact, he builds a legacy of innovation, education, and scientific integrity. Prof. Theocharis is a compelling candidate for the Best Researcher Award, combining scholarly brilliance with global influence and community service 🏆.

Chun Xu | Interdisciplinary Mathematics | Best Researcher Award

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Prof. Dr. Chun Xu | Interdisciplinary Mathematics | Best Researcher Award

Professor at Xinjiang University of Finance & Economics, China

Prof. Dr. Xu Chun 🎓, a distinguished scholar and PhD supervisor in the realm of Big Data Analysis and Applications 📊💡, exemplifies excellence in research and education. Earning his PhD from the University of Chinese Academy of Sciences in 2018, he has rapidly risen as a thought leader, recognized through the prestigious “Tianshan Talent” program 🌟. With over 40 impactful publications in leading journals 📚 and leadership of 13 major research projects, including those under the National Natural Science Foundation, Prof. Xu has significantly advanced data-driven innovation and technology. His accolades include top honors in national teaching and academic paper competitions 🏅, reflecting a rare fusion of pedagogical brilliance and scientific depth. Passionate about discovery, mentorship, and cross-disciplinary growth, he continues to inspire the scientific community with his visionary work and collaborative spirit 🤝. Prof. Xu Chun stands as a beacon of innovation, shaping the future of intelligent data applications.

Professional Profile 

Scopus Profile

🎓 Education

Prof. Dr. Xu Chun’s academic path is a story of dedication and precision. He earned his PhD in Computer Application Technology from the prestigious University of Chinese Academy of Sciences in 2018 🎓, laying a firm foundation in the ever-evolving domain of computational intelligence and big data. His education is steeped in rigorous analytical training, advanced machine learning, and algorithmic design. This academic odyssey empowered him with a multifaceted understanding of the data ecosystem—from raw datasets to real-world applications 📈. His scholarly journey reflects a commitment to lifelong learning, academic excellence, and technical innovation. With each milestone, Prof. Xu has cemented himself as a profound thinker, ready to tackle future challenges through a lens of scientific curiosity and intellectual precision 🧠🔍.

💼 Professional Experience

With an illustrious career marked by leadership and innovation, Prof. Xu Chun currently serves as a full Professor and PhD supervisor 🧑‍🏫. Over the years, he has cultivated an ecosystem of excellence in data science, guiding numerous doctoral students and researchers toward impactful academic and industry pursuits. He has successfully led 13 competitive projects including those from the National Natural Science Foundation, Xinjiang Aid Program, and the Xinjiang Natural Science Foundation 🔬💼. His professional experience combines high-stakes research management with grassroots mentorship, establishing him as a pillar of scholarly progress. Moreover, his role in academic development within the Xinjiang Uygur Autonomous Region has contributed significantly to regional scientific advancement 🧭. Prof. Xu is not only an academic leader but a visionary orchestrator of computational innovation—bridging institutional goals with the broader tech-research frontier. 🌐

🔬 Research Interest

Prof. Xu Chun’s research interests orbit around Big Data Analysis and Applications, an ever-expanding universe of digital insight 🚀📊. His work explores the convergence of algorithmic intelligence, machine learning, and large-scale data systems—striving to make sense of complexity through structured, meaningful interpretations. He delves into predictive analytics, pattern recognition, and intelligent computing, with a keen focus on real-world utility and interdisciplinary crossover 🌉. Xu’s research thrives on innovation—constantly pushing boundaries to unlock new knowledge and scalable solutions. Whether it’s optimizing data flow, improving data-driven decision-making, or constructing intelligent frameworks for industry applications, his research reflects both precision and creativity. Passionate about turning raw data into refined intelligence, Prof. Xu continues to illuminate pathways where technology, theory, and transformation intersect. 🧠💾✨

🏅 Awards and Honors

Prof. Xu Chun’s brilliance has been widely acknowledged through numerous accolades 🏆. A recipient of the esteemed “Tianshan Talent” award in the Xinjiang Uygur Autonomous Region 🌟, he has been recognized for both his intellectual depth and his regional impact. He has also earned the Third Prize in the National College Young Teachers Teaching Competition 🥉, and Second Prizes in the 9th and 12th Xinjiang Natural Science Outstanding Academic Papers 🥈—a testament to his scholarly excellence and research clarity. These honors underscore his rare ability to fuse research with education, thought with action, and theory with real-world benefit 📜💡. His achievements are more than accolades—they are milestones that reflect a lifelong devotion to discovery, teaching, and the betterment of society through scientific insight. Xu stands as an emblem of academic honor and progressive innovation in China’s research landscape. 🇨🇳🌐

🧩 Conclusion

Prof. Dr. Xu Chun stands at the confluence of intellect, innovation, and influence 🧠🌟. With a strong academic foundation, a wealth of professional experience, and a laser focus on future-forward research, he epitomizes the modern scientific leader. His ability to bridge data science theory with real-world application not only inspires his peers but also empowers the next generation of thinkers and doers 📚🤝. The impact of his work ripples across academic communities and technological frontiers alike, establishing him as an ideal candidate for the Best Researcher Award 🏅. Through his awards, projects, and publications, he has created a legacy grounded in excellence and guided by vision. As a champion of knowledge and a cultivator of potential, Prof. Xu Chun’s contributions transcend boundaries—making him not only a researcher of the present but a pioneer for tomorrow’s scientific world 🌍🚀.

Publications Top Notes